Affiliation:
1. School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Abstract
The
coi1
mutation defines an
Arabidopsis
gene required for response to jasmonates, which regulate defense against insects and pathogens, wound healing, and pollen fertility. The wild-type allele,
COI1
, was mapped to a 90-kilobase genomic fragment and located by complementation of
coi1-1
mutants. The predicted amino acid sequence of the COI1 protein contains 16 leucine-rich repeats and an F-box motif. It has similarity to the F-box proteins
Arabidopsis
TIR1, human Skp2, and yeast Grr1, which appear to function by targeting repressor proteins for removal by ubiquitination.
Publisher
American Association for the Advancement of Science (AAAS)
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