Linkage Disequilibrium and Recombination in Hominid Mitochondrial DNA-Reference-Cited by-同舟云学术

Linkage Disequilibrium and Recombination in Hominid Mitochondrial DNA

Published:1999-12-24 Issue:5449 Volume:286 Page:2524-2525
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Awadalla Philip¹,Eyre-Walker Adam²,Smith John Maynard²

Affiliation:

1. Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 1JT, UK.

2. Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton BN1 9QG, UK.

Abstract

The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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