Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer

Author:

Lewis Mitchell1,Chang Geoffrey1,Horton Nancy C.2,Kercher Michele A.2,Pace Helen C.2,Schumacher Maria A.3,Brennan Richard G.3,Lu Ponzy2

Affiliation:

1. M. Lewis and G. Chang are in the Johnson Research Foundation and Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.

2. N. C. Horton, M. A. Kercher, H. C. Pace, and P. Lu are in the Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA.

3. M. A. Schumacher and R. G. Brennan are in the Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, OR 97201, USA.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference75 articles.

1. ADHYA S, ANNU REV GENET 23, 207 (1989).

2. DIMER-TO-TETRAMER ASSEMBLY OF LAC REPRESSOR INVOLVES A LEUCINE HEPTAD REPEAT;ALBERTI S;NEW BIOLOGIST,1991

3. PHYSICAL-PROPERTIES OF DNA INVIVO AS PROBED BY THE LENGTH DEPENDENCE OF THE LAC OPERATOR LOOPING PROCESS;BELLOMY R. G.;BIOCHEMISTRY,1988

4. CLONING AND CHARACTERIZATION OF SEVERAL DOMINANT-NEGATIVE AND TIGHT-BINDING MUTANTS OF LAC REPRESSOR;BETZ L. J.;GENE,1986

5. AMINO-ACID SEQUENCE OF LAC REPRESSOR;BEYREUTHER K;PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,1973

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