A Metalloprotease Disintegrin That Controls Cell Migration in Caenorhabditis elegans-Reference-Cited by-同舟云学术

A Metalloprotease Disintegrin That Controls Cell Migration in Caenorhabditis elegans

Published:2000-06-23 Issue:5474 Volume:288 Page:2205-2208
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Nishiwaki Kiyoji¹,Hisamoto Naoki²,Matsumoto Kunihiro²

Affiliation:

1. PRESTO, Japan Science and Technology Corporation and Fundamental Research Laboratories, NEC Corporation, Miyukigaoka, Tsukuba 305-8501, Japan.

2. Department of Molecular Biology, Graduate School of Science, Nagoya University, and CREST, Japan Science and Technology Corporation, Chikusa-ku, Nagoya 464-8602, Japan.

Abstract

In Caenorhabditis elegans , the gonad acquires two U-shaped arms by the directed migration of its distal tip cells (DTCs) along the body wall basement membranes. Correct migration of DTCs requires the mig-17 gene, which encodes a member of the metalloprotease-disintegrin protein family. The MIG-17 protein is secreted from muscle cells of the body wall and localizes in the basement membranes of gonad. This localization is dependent on the disintegrin-like domain of MIG-17 and its catalytic activity. These results suggest that the MIG-17 metalloprotease directs migration of DTCs by remodeling the basement membrane.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference25 articles.

1. Kimble J. E., White J. G., Dev. Biol. 81, 208 (1981);

2. Hedgecock E. M., Culotti J. G., Hall D. H., Stern B. D., Development 100, 365 (1987).

3. Nishiwaki K., Genetics 152, 985 (1999).

4. Caenorhabditis elegans hermaphrodites were observed using a Zeiss Axioplan microscope equipped with a Plan 100 objective and Nomarski differential interference contrast optics. Images were captured with a Hamamatsu Photonics C5810 Color Chilled 3-CCD Camera connected to a Macintosh G3 computer.

5. The mig-17 gene was mapped to the right of the Bergerac Tc1 polymorphism bP1 on linkage group V by polymerase chain reaction–sequence tagged site (PCR-STS) mapping. Three-factor mapping placed mig-17 between bP1 and daf-11. Two cosmid clones T26H10 and F57B7 were found to rescue mig-17(k174). Four coding regions were predicted to lie within the region common to T26H10 and F57B7 by the C. elegans genome sequencing consortium computer analysis. The 5′ terminus of the mig-17 message was analyzed using the 5′ RACE System (rapid amplification of cDNA ends; Life Technologies).

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