Interferon-α But Not AZT Suppresses HIV Expression in Chronically Infected Cell Lines

Author:

Poli Guido1,Orenstein Jan M.2,Kinter Audrey1,Folks Thomas M.1,Fauci Anthony S.1

Affiliation:

1. Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.

2. Department of Pathology, George Washington University Medical Center, Washington, DC 200-07.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference53 articles.

1. BENDER, B.S., IMPAIRED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXIC ACTIVITY IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME, CLINICAL AND EXPERIMENTAL IMMUNOLOGY 64: 166 (1986).

2. CLOUSE, K.A., MONOKINE REGULATION OF HUMAN IMMUNODEFICIENCY VIRUS-1 EXPRESSION IN A CHRONICALLY INFECTED HUMAN T-CELL CLONE, JOURNAL OF IMMUNOLOGY 142: 431 (1989).

3. DOLEI, A, DIRECT AND CELL-MEDIATED EFFECTS OF INTERFERON-ALPHA AND INTERFERON-GAMMA ON CELLS CHRONICALLY INFECTED WITH HTLV-III, JOURNAL OF INTERFERON RESEARCH 6: 543 (1986).

4. The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

5. FISCHL, M.A., THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL, NEW ENGLAND JOURNAL OF MEDICINE 317: 185 (1987).

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