MARF1 Regulates Essential Oogenic Processes in Mice-Reference-Cited by-同舟云学术

MARF1 Regulates Essential Oogenic Processes in Mice

Published:2012-03-23 Issue:6075 Volume:335 Page:1496-1499
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Su You-Qiang¹,Sugiura Koji¹,Sun Fengyun¹,Pendola Janice K.¹,Cox Gregory A.¹,Handel Mary Ann¹,Schimenti John C.²,Eppig John J.¹

Affiliation:

1. The Jackson Laboratory, Bar Harbor, ME 04609, USA.

2. College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

Abstract

Mistress of Meiosis Meiosis is essential for proper distribution of maternal chromosomes to eggs during oogenesis. Su et al. (p. 1496 ) identified a gene, meiosis arrest female 1 ( Marf1 ), which is indispensable for meiosis and other oogenic processes. In mice, Marf1 mutations resulted in meiotic arrest and an increase in nuclear DNA double-strand breaks, phenotypes linked to up-regulated levels of specific messenger RNAs (mRNA). These findings place MARF1 as a key regulator of mammalian female fertility through its integration of oocyte mRNA homeostasis, meiosis, and maintenance of genomic integrity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference29 articles.

1. Coordination of nuclear and cytoplasmic oocyte maturation in eutherian mammals

2. ART failure: oocyte contributions to unsuccessful fertilization

3. Transposable elements in the mammalian germline: a comfortable niche or a deadly trap?

4. OST-HTH: a novel predicted RNA-binding domain

5. LOTUS, a new domain associated with small RNA pathways in the germline

Cited by 91 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comparative genomic studies of Tomtom and Nuaimi sheep breeds of Bahrain, and Asian and European sheep breeds revealed selection signatures;2024-03-04

2. Genomics of post-bottleneck recovery in the northern elephant seal;Nature Ecology & Evolution;2024-02-21

3. Diverse roles of biomolecular condensation in eukaryotic translational regulation;RNA Biology;2023-10-31

4. Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest;eLife;2023-06-19

5. LSM14B is an Oocyte‐Specific RNA‐Binding Protein Indispensable for Maternal mRNA Metabolism and Oocyte Development in Mice;Advanced Science;2023-04-21