Fear Erasure in Mice Requires Synergy Between Antidepressant Drugs and Extinction Training

Author:

Karpova Nina N.1,Pickenhagen Anouchka2,Lindholm Jesse13,Tiraboschi Ettore1,Kulesskaya Natalia1,Ágústsdóttir Arna1,Antila Hanna1,Popova Dina1,Akamine Yumiko1,Sullivan Regina2,Hen René4,Drew Liam J.4,Castrén Eero14

Affiliation:

1. Sigrid Jusélius Laboratory, Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland.

2. Emotional Brain Institute Nathan Kline Institute, Child and Adolescent Psychiatry, New York University Medical Center, New York, NY 10016, USA.

3. Department of Biosciences and Physiology, University of Helsinki, 00014 Helsinki, Finland.

4. Department of Psychiatry and Neuroscience, Columbia University, New York, NY 10032, USA.

Abstract

Long-term loss of fearful memories can be achieved through a combination of antidepressant drugs and exposure therapy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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