Reversible Molecular Adsorption Based on Multiple-Point Interaction by Shrinkable Gels-Reference-Cited by-同舟云学术

Reversible Molecular Adsorption Based on Multiple-Point Interaction by Shrinkable Gels

Published:1999-11-19 Issue:5444 Volume:286 Page:1543-1545
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Oya Taro¹,Enoki Takashi¹,Grosberg Alexander Yu.¹,Masamune Satoru²,Sakiyama Takaharu¹,Takeoka Yukikazu¹,Tanaka Kazunori¹,Wang Guoqiang¹,Yilmaz Yasar¹,Feld Michael S.³,Dasari Ramachandra³,Tanaka Toyoichi¹

Affiliation:

1. Department of Physics and Center for Materials Science and Engineering,

2. Department of Chemistry,

3. George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference7 articles.

1. Schild H. G., Prog. Polym. Sci. 17, 163 (1992).

2. Hirotsu S., Hirokawa Y., Tanaka T., J. Chem. Phys. 87, 1392 (1987).

3. Ricka J., Tanaka T., Macromolecules 18, 83 (1984).

4. There have been works on molecular adsorption in particular on its dependence on phase states of polymers and gels. These studies mostly used nonspecific hydrophobic interaction. The affinity changes in response to polymer density changes triggered by temperature. See for example

5. Yamato M., et al., Connect. Tissue 31, 13 (1999).

Cited by 209 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimal conditions for the use of polyrotaxane as a cross-linker in preparing elastomers with high toughnesses;Polymer Journal;2024-02-28

2. Engineering Temperature-Responsive Polymer Nanoparticles that Load and Release Paclitaxel, a Low-Molecular-Weight Anticancer Drug;ACS Omega;2023-12-27

3. Imprinted Hydrogel Nanoparticles for Protein Biosensing: A Review;ACS Sensors;2023-08-09

4. Cooling-induced, localized release of cytotoxic peptides from engineered polymer nanoparticles in living mice for cancer therapy;Journal of Controlled Release;2023-03

5. Anisotropic Responses with Cation Selectivity in Hierarchically Ordered Polysaccharide Networks;ACS Applied Polymer Materials;2022-09-01