Affiliation:
1. New York University, Department of Biology, Center for Developmental Genetics, 100 Washington Square East, New York, NY 10003, USA.
Abstract
The long-germ mode of embryogenesis, in which segments arise simultaneously along the anteriorposterior axis, has evolved several times in different lineages of the holometabolous, or fully metamorphosing, insects.
Drosophila
's long-germ fate map is established largely by the activity of the dipteran-specific Bicoid (Bcd) morphogen gradient, which operates both instructively and permissively to accomplish anterior patterning. By contrast, all nondipteran long-germ insects must achieve anterior patterning independently of
bcd
. We show that
bcd
's permissive function is mimicked in the wasp by a maternal repression system in which anterior localization of the wasp ortholog of
giant
represses anterior expression of the trunk gap genes so that head and thorax can properly form.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
53 articles.
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