Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide-Reference-Cited by-同舟云学术

Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide

Published:2011-07-22 Issue:6041 Volume:333 Page:463-467
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Tonkin Michelle L.¹,Roques Magali²,Lamarque Mauld H.²,Pugnière Martine³,Douguet Dominique⁴,Crawford Joanna¹,Lebrun Maryse²,Boulanger Martin J.¹

Affiliation:

1. Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada.

2. UMR 5235 CNRS, Université de Montpellier 2, 34095 Montpellier, France.

3. Institut de Recherche en Cancerologie de Montpellier, INSERM U896, 34298 Montpellier, France.

4. CNRS UMR6097-Université Nice-Sophia Antipolis 660, 06560 Valbonne, France.

Abstract

The structure of a eukaryotic pathogen adhesin bound to its receptor provides a basis for design of therapeutics.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

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2. Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts;Carruthers V. B.;Eur. J. Cell Biol.,1997

3. Kiss and spit: the dual roles of Toxoplasma rhoptries

4. Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion

5. The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

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