A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling-Reference-Cited by-同舟云学术

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

Published:2011-06-10 Issue:6035 Volume:332 Page:1313-1317
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Cotta-Ramusino Cecilia¹,McDonald E. Robert¹,Hurov Kristen¹,Sowa Mathew E.²,Harper J. Wade²,Elledge Stephen J.¹

Affiliation:

1. Department of Genetics, Harvard University Medical School, Howard Hughes Medical Institute, Division of Genetics, Brigham and Women’s Hospital, Harvard University Medical School, Boston, MA 02115, USA.

2. Department of Pathology, Harvard University Medical School, Boston, MA 02115, USA.

Abstract

A screen identifies proteins not previously known to function in protecting cells from DNA damage.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

1. The DNA Damage Response: Making It Safe to Play with Knives

2. ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

3. Profiling of UV-induced ATM/ATR signaling pathways

4. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

5. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

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