Signal Transduction and the Control of Gene Expression-Reference-Cited by-同舟云学术

Signal Transduction and the Control of Gene Expression

Published:2002-02 Issue:5556 Volume:295 Page:813-818
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Brivanlou Ali H.¹,Darnell James E.²

Affiliation:

1. Laboratory of Molecular Vertebrate Embryology,

2. Laboratory of Molecular Cell Biology, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

Abstract

More than 2000 transcription factors are encoded in the human genome. Such proteins have often been classified according to common structural elements. But because transcription factors evolved in the service of biologic function, we propose an alternative grouping of eukaryotic transcription factors on the basis of characteristics that describe their roles within cellular regulatory circuits.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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