Tuning the Activation Threshold of a Kinase Network by Nested Feedback Loops-Reference-Cited by-同舟云学术

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Tuning the Activation Threshold of a Kinase Network by Nested Feedback Loops

Published:2009-04-24 Issue:5926 Volume:324 Page:509-512
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Justman Quincey A.¹²,Serber Zach³,Ferrell James E.³,El-Samad Hana⁴,Shokat Kevan M.²

Affiliation:

1. Graduate Group in Biophysics, University of California, San Francisco, CA 94158, USA.

2. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.

3. Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305–5174, USA.

4. Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.

Abstract

Interacting negative feedback loops control the sensitivity of amphibian oocytes to the hormone progesterone.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

1. Regulation of the meiotic cell cycle in oocytes

2. Cell-cycle control during meiotic maturation

3. Synthesis and function of mos: The control switch of vertebrate oocyte meiosis

4. The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes

5. A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision

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