Assessing the global threat from Zika virus-Reference-Cited by-同舟云学术

Assessing the global threat from Zika virus

Published:2016-08-12 Issue:6300 Volume:353 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lessler Justin¹,Chaisson Lelia H.¹,Kucirka Lauren M.¹²,Bi Qifang¹,Grantz Kyra³,Salje Henrik¹⁴,Carcelen Andrea C.⁵,Ott Cassandra T.¹,Sheffield Jeanne S.⁶,Ferguson Neil M.⁷,Cummings Derek A. T.³,Metcalf C. Jessica E.⁸⁹,Rodriguez-Barraquer Isabel¹

Affiliation:

1. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

2. Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

3. Department of Biology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.

4. Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France.

5. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

6. Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

7. Department of Medicine, School of Public Health, Imperial College London, London, UK.

8. Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.

9. Office of Population Research, Princeton University, Princeton, NJ, USA.

Abstract

Global spread of Zika virus Zika virus was identified in Uganda in 1947; since then, it has enveloped the tropics, causing disease of varying severity. Lessler et al. review the historical literature to remind us that Zika's neurotropism was observed in mice even before clinical case reports in Nigeria in 1953. What determines the clinical manifestations; how local conditions, vectors, genetics, and wild hosts affect transmission and geographical spread; what the best control strategy is; and how to develop effective drugs, vaccines, and diagnostics are all critical questions that are begging for data. Science , this issue p. 663

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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