Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

Author:

Whitmarsh Alan J.1,Shore Paul2,Sharrocks Andrew D.2,Davis Roger J.1

Affiliation:

1. oward Hughes Medical Institute, and Program in Molecular Medicine, Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

2. Department of Biochemistry and Genetics, The Medical School, University of Newcastle-upon-Tyne, NE2 4HH, UK.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference43 articles.

1. ANDERSSON, S, CLONING, STRUCTURE, AND EXPRESSION OF THE MITOCHONDRIAL CYTOCHROME-P-450 STEROL 26-HYDROXYLASE, A BILE-ACID BIOSYNTHETIC ENZYME, JOURNAL OF BIOLOGICAL CHEMISTRY 264: 8222 (1989).

2. The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

3. BUSCHER, M, ACTIVATION OF THE C-FOS GENE BY UV AND PHORBOL ESTER - DIFFERENT SIGNAL TRANSDUCTION PATHWAYS CONVERGE TO THE SAME ENHANCER ELEMENT, ONCOGENE 3: 301 (1988).

4. CANO, E, ANISOMYCIN-ACTIVATED PROTEIN KINASE-P45 AND KINASE-P55 BUT NOT MITOGEN-ACTIVATED PROTEIN KINASE-ERK-1 AND KINASE-ERK-2 ARE IMPLICATED IN THE INDUCTION OF C-FOS AND C-JUN, MOLECULAR AND CELLULAR BIOLOGY 14: 7352 (1994).

5. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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