Genomic evidence for the Pleistocene and recent population history of Native Americans-Reference-Cited by-同舟云学术

Genomic evidence for the Pleistocene and recent population history of Native Americans

Published:2015-08-21 Issue:6250 Volume:349 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Raghavan Maanasa¹,Steinrücken Matthias²³⁴,Harris Kelley⁵,Schiffels Stephan⁶,Rasmussen Simon⁷,DeGiorgio Michael⁸,Albrechtsen Anders⁹,Valdiosera Cristina¹¹⁰,Ávila-Arcos María C.¹¹¹,Malaspinas Anna-Sapfo¹,Eriksson Anders¹²¹³,Moltke Ida⁹,Metspalu Mait¹⁴¹⁵,Homburger Julian R.¹¹,Wall Jeff¹⁶,Cornejo Omar E.¹⁷,Moreno-Mayar J. Víctor¹,Korneliussen Thorfinn S.¹,Pierre Tracey¹,Rasmussen Morten¹¹¹,Campos Paula F.¹¹⁸,Damgaard Peter de Barros¹,Allentoft Morten E.¹,Lindo John¹⁹,Metspalu Ene¹⁴¹⁵,Rodríguez-Varela Ricardo²⁰,Mansilla Josefina²¹,Henrickson Celeste²²,Seguin-Orlando Andaine¹,Malmström Helena²³,Stafford Thomas¹²⁴,Shringarpure Suyash S.¹¹,Moreno-Estrada Andrés¹¹²⁵,Karmin Monika¹⁴¹⁵,Tambets Kristiina¹⁴,Bergström Anders⁶,Xue Yali⁶,Warmuth Vera²⁶²⁷,Friend Andrew D.²⁸,Singarayer Joy²⁹,Valdes Paul³⁰,Balloux Francois²⁶,Leboreiro Ilán²¹,Vera Jose Luis³¹,Rangel-Villalobos Hector³²,Pettener Davide³³,Luiselli Donata³³,Davis Loren G.³⁴,Heyer Evelyne³⁵,Zollikofer Christoph P. E.³⁶,Ponce de León Marcia S.³⁶,Smith Colin I.¹⁰,Grimes Vaughan³⁷³⁸,Pike Kelly-Anne³⁷,Deal Michael³⁷,Fuller Benjamin T.³⁹,Arriaza Bernardo⁴⁰,Standen Vivien⁴¹,Luz Maria F.⁴²,Ricaut Francois⁴³,Guidon Niede⁴²,Osipova Ludmila⁴⁴⁴⁵,Voevoda Mikhail I.⁴⁴⁴⁶⁴⁷,Posukh Olga L.⁴⁴⁴⁵,Balanovsky Oleg⁴⁸⁴⁹,Lavryashina Maria⁵⁰,Bogunov Yuri⁴⁸,Khusnutdinova Elza⁵¹⁵²,Gubina Marina⁴⁴,Balanovska Elena⁴⁹,Fedorova Sardana⁵³⁵⁴,Litvinov Sergey¹⁴⁵¹,Malyarchuk Boris⁵⁵,Derenko Miroslava⁵⁵,Mosher M. J.⁵⁶,Archer David⁵⁷,Cybulski Jerome⁵⁸⁵⁹⁶⁰,Petzelt Barbara⁶¹,Mitchell Joycelynn⁶¹,Worl Rosita⁶²,Norman Paul J.⁶³,Parham Peter⁶³,Kemp Brian M.¹⁷⁶⁴,Kivisild Toomas¹⁴⁶⁵,Tyler-Smith Chris⁶,Sandhu Manjinder S.⁶⁶⁶,Crawford Michael⁶⁷,Villems Richard¹⁴¹⁵,Smith David Glenn⁶⁸,Waters Michael R.⁶⁹⁷⁰⁷¹,Goebel Ted⁶⁹,Johnson John R.⁷²,Malhi Ripan S.¹⁹⁷³,Jakobsson Mattias²³,Meltzer David J.¹⁷⁴,Manica Andrea¹²,Durbin Richard⁶,Bustamante Carlos D.¹¹,Song Yun S.²³⁷⁵,Nielsen Rasmus⁷⁵,Willerslev Eske¹

Affiliation:

1. Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5–7, 1350 Copenhagen, Denmark.

2. Computer Science Division, University of California, Berkeley, Berkeley, CA 94720, USA.

3. Department of Statistics, University of California, Berkeley, Berkeley, CA 94720, USA.

4. Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA 01003, USA.

5. Department of Mathematics, University of California, Berkeley, Berkeley, CA 94720, USA.

6. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.

7. Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet, Building 208, 2800 Kongens Lyngby, Denmark.

8. Departments of Biology and Statistics, Pennsylvania State University, 502 Wartik Laboratory, University Park, PA 16802, USA.

9. The Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark.

10. Department of Archaeology and History, La Trobe University, Melbourne, Victoria 3086, Australia.

11. Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA 94305, USA.

12. Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.

13. Integrative Systems Biology Laboratory, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.

14. Estonian Biocentre, Evolutionary Biology Group, Tartu 51010, Estonia.

15. Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.

16. Institute for Human Genetics, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

17. School of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA 99164, USA.

18. Centro de Investigación en Ciencias del Mar y Limnología/Centro Interdisciplinar de Investigação Marinha e Ambiental, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas 289, 4050-123 Porto, Portugal.

19. Department of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL 61801, USA.

20. Centro Mixto, Universidad Complutense de Madrid–Instituto de Salud Carlos III de Evolución y Comportamiento Humano, Madrid, Spain.

21. Instituto Nacional de Antropología e Historia, Moneda 13, Centro, Cuauhtémoc, 06060 Mexico City, Mexico.

22. University of Utah, Department of Anthropology, 270 S 1400 E, Salt Lake City, UT 84112, USA.

23. Department of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden.

24. Acceleration Mass Spectrometry 14C Dating Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000 Aarhus, Denmark.

25. Laboratorio Nacional de Genómica para la Biodiversidad (LANGEBIO), Centro de Investigación y de Estudios Avanzados, Irapuato, Guanajuato 36821, Mexico.

26. Genetics Institute, University College London, Gower Street, London WC1E 6BT, UK.

27. Evolutionsbiologiskt Centrum, Norbyvägen 18D, 75236 Uppsala, Sweden.

28. Department of Geography, University of Cambridge, Downing Place, Cambridge CB2 3EN, UK.

29. Centre for Past Climate Change and Department of Meteorology, University of Reading, Earley Gate, Post Office Box 243, Reading, UK.

30. School of Geographical Sciences, University Road, Clifton, Bristol BS8 1SS, UK.

31. Escuela Nacional de AntropologÍa e Historia, Periférico Sur y Zapote s/n Colonia Isidro Fabela, Tlalpan, Isidro Fabela, 14030 Mexico City, Mexico.

32. Instituto de Investigación en Genética Molecular, Universidad de Guadalajara, Ocotlán, Mexico.

33. Dipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Università di Bologna, Via Selmi 3, 40126 Bologna, Italy.

34. Department of Anthropology, Oregon State University, 238 Waldo Hall, Corvallis, OR 97331 USA.

35. Museum National d'Histoire Naturelle, CNRS, Université Paris 7 Diderot, Sorbonne Paris Cité, Sorbonne Universités, Unité Eco-Anthropologie et Ethnobiologie (UMR7206), Paris, France.

36. Anthropological Institute and Museum, University of Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.

37. Department of Archaeology, Memorial University, Queen’s College, 210 Prince Philip Drive, St. John’s, Newfoundland A1C 5S7, Canada.

38. Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany.

39. Department of Earth System Science, University of California, Irvine, Keck Carbon Cycle Accelerator Mass Spectrometry Group, B321 Croul Hall, Irvine, CA 92697, USA.

40. Instituto de Alta Investigación, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile.

41. Departamento de Antropologia, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile.

42. Fundação Museu do Homem Americano, Centro Cultural Sérgio Motta, Campestre, 64770-000 Sao Raimundo Nonato, Brazil.

43. Laboratoire d’Anthropologie Moléculaire et Imagérie de Synthèse UMR-5288, CNRS, Université de Toulouse, 31073 Toulouse, France.

44. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, 630090 Novosibirsk, Russia.

45. Novosibirsk State University, 2 Pirogova Street, 630090 Novosibirsk, Russia.

46. Institute of Internal Medicine, Siberian Branch of RAS, 175/1 ul. B. Bogatkova, Novosibirsk 630089, Russia.

47. Novosibirsk State University, Laboratory of Molecular Epidemiology and Bioinformatics, 630090 Novosibirsk, Russia.

48. Vavilov Institute of General Genetics, Gubkina 3, 119333 Moscow, Russia.

49. Research Centre for Medical Genetics, Moskvorechie 1, 115478 Moscow, Russia.

50. Kemerovo State University, Krasnaya 3, 650000 Kemerovo, Russia.

51. Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, 450054 Ufa, Russia.

52. Department of Genetics and Fundamental Medicine, Bashkir State University, Zaki Validi 32, 450076 Ufa, Russia.

53. Department of Molecular Genetics, Yakut Scientific Centre of Complex Medical Problems, Sergelyahskoe Shosse 4, 677010 Yakutsk, Russia.

54. Laboratory of Molecular Biology, Institute of Natural Sciences, M. K. Ammosov North-Eastern Federal University, 677000 Yakutsk, Russia.

55. Institute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan 685000, Russia.

56. Department of Anthropology, Western Washington University, Bellingham, WA 98225, USA.

57. Department of Anthropology, Northwest Community College, 353 Fifth Street, Prince Rupert, British Columbia V8J 3L6, Canada.

58. Canadian Museum of History, 100 Rue Laurier, Gatineau, Quebec K1A 0M8, Canada.

59. University of Western Ontario, London, Ontario N6A 3K7, Canada.

60. Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.

61. Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC V8J 3P6, Canada.

62. Sealaska Heritage Institute, 105 S. Seward Street, Juneau, AK 99801, USA.

63. Department of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA 94305-5126, USA.

64. Department of Anthropology, Washington State University, Pullman, WA 99163, USA.

65. Division of Biological Anthropology, University of Cambridge, Henry Wellcome Building, Fitzwilliam Street, Cambridge CB2 1QH, UK.

66. Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

67. Laboratory of Biological Anthropology, University of Kansas, 1415 Jayhawk Boulevard, 622 Fraser Hall, Lawrence, KS 66045, USA.

68. Molecular Anthropology Laboratory, 209 Young Hall, Department of Anthropology, University of California, One Shields Avenue, Davis, CA 95616, USA.

69. Center for the Study of the First Americans, Texas A&M University, College Station, TX 77843-4352, USA.

70. Department of Anthropology, Texas A&M University, College Station, TX 77843-4352, USA.

71. Department of Geography, Texas A&M University, College Station, TX 77843-4352, USA.

72. Santa Barbara Museum of Natural History, 2559 Puesta del Sol, Santa Barbara, CA 93105, USA.

73. Carle R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

74. Department of Anthropology, Southern Methodist University, Dallas, TX 75275, USA.

75. Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building 3140, Berkeley, CA 94720, USA.

Abstract

Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier than 23,000 years ago from Siberian ancestors. Amerindians and Athabascans originated from a single population, splitting approximately 13,000 years ago. Science , this issue 10.1126/science.aab3884

Funder

National Science Foundation

National Institutes of Health

Social Science Research Council of Canada

Wenner-Gren Foundations

Wellcome Trust

Washington State University

European Research Council

Biotechnology and Biological Sciences Research Council

Australian Research Council

French National Research Agency

Swiss National Science Foundation