Integration of omic networks in a developmental atlas of maize

Abstract

Patterns of development regulation within tissues Expression of a given gene at the RNA level does not always correlate with expression at the protein level for many organisms. Walley et al. have built an integrated atlas of gene expression and regulatory networks in developing maize, using the same tissue samples to measure the transcriptome, proteome, and phosphoproteome. Coexpression networks from the transcriptome and proteome showed little overlap with each other, even though they showed enrichment of similar pathways. Integration of mRNA, protein, and phosphoprotein data sets improved the predictive power of the gene regulatory networks. Science , this issue p. 814