Adult Neural Function Requires MeCP2-Reference-Cited by-同舟云学术

Adult Neural Function Requires MeCP2

Published:2011-07-08 Issue:6039 Volume:333 Page:186-186
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

McGraw Christopher M.¹²,Samaco Rodney C.³,Zoghbi Huda Y.¹³⁴

Affiliation:

1. Program in Developmental Biology, Baylor College of Medicine, and Jan and Dan Duncan Neurological Research Institute, Houston, TX 77030, USA.

2. Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA.

3. Department of Molecular and Human Genetics, Baylor College of Medicine, and Jan and Dan Duncan Neurological Research Institute, Houston, TX 77030, USA.

4. Department of Neuroscience and Howard Hughes Medical Institute, Baylor College of Medicine, and Jan and Dan Duncan Neurological Research Institute, Houston, TX 77030, USA.

Abstract

An epigenetic program regulated by MeCP2 needs to be maintained throughout life for normal neurological function.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference6 articles.

1. The Story of Rett Syndrome: From Clinic to Neurobiology

2. Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

3. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

4. Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

5. MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

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