Imaging Local Electrochemical Current via Surface Plasmon Resonance

Abstract

An Electrochemical Landscape Electrochemical detection is an analytical method that has been used for a wide range of purposes, including trace chemical analysis, glucose and neurotransmitter monitoring, DNA and protein detection, and electrocatalysis. Scanning electrochemical microscopy maps changes in the local electrochemical current along a surface in a serial way, but serial probing can disrupt the process under study. Shan et al. (p. 1363 ) show that optical measurements of surface plasmon resonances can be used as a less disruptive way of determining the concentration of electrochemically active species on gold-coated glass slides and their current density. This method can be used for a wide range of applications from analyzing DNA and protein microarrays and enzyme-amplified biosensors to probing the activities of cells.