Reduction in Size of the Myotonic Dystrophy Trinucleotide Repeat Mutation During Transmission

Author:

O'Hoy Kim L.1,Tsilfidis Catherine1,Mahadevan Mani S.1,Neville Catherine E.1,Barceló Juana1,Hunter Alasdair G. W.2,Korneluk Robert G.2

Affiliation:

1. Department of Microbiology and Immunology, University of Ottawa, Canada K1 H 8M5.

2. Division of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Canada K1 H 8L1.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference25 articles.

1. BISHOP, D.K., REPAIR OF HETERODUPLEX PLASMID DNA AFTER TRANSFORMATION INTO SACCHAROMYCES-CEREVISIAE, MOLECULAR AND CELLULAR BIOLOGY 6: 3401 (1986).

2. Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

3. FU, Y.H., CELL 67: 1 (1991).

4. An Unstable Triplet Repeat in a Gene Related to Myotonic Muscular Dystrophy

5. Harper P. S. Myotonic Dystrophy 2 (1989).

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