Response to Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI”-Reference-Cited by-同舟云学术

Response to Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI”

Published:2010-04-16 Issue:5976 Volume:328 Page:309-309
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Minzenberg Michael J.¹,Watrous Andrew J.¹,Yoon Jong H.¹,La Christian¹,Ursu Stefan¹,Carter Cameron S.¹

Affiliation:

1. Department of Psychiatry, University of California, Davis, School of Medicine, Sacramento, CA 95817, USA.

Abstract

Contrary to the arguments put forth by Astafiev et al ., our new analyses and high-resolution replication show that modulation of brain activity by the cognitive enhancing drug modafinil indeed localizes to the locus coeruleus. The authors’ critical stance regarding blood oxygen level–dependent imaging in the brainstem does not follow from their data.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference16 articles.

1. Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI

2. Comment on “Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI” and “Homeostatic Sleep Pressure and Responses to Sustained Attention in the Suprachiasmatic Area”

3. G. Paxinos X. Huang Atlas of the Human Brainstem (Academic Press San Diego CA 1995).

4. T. P. Naidich et al . Duvernoy’s Atlas of the Human Brain Stem and Cerebellum: High-Field MRI Surface Anatomy Internal Structure Vascularization and 3D Sectional Anatomy. (Springer-Verlag Vienna 2009).

5. S. J. DeArmond M. M. Fusco M. M. Dewey Structure of the Human Brain. A Photographic Atlas (Oxford Univ. Press New York ed. 3 1989).

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