Temperature Sex Reversal Implies Sex Gene Dosage in a Reptile-Reference-Cited by-同舟云学术

Temperature Sex Reversal Implies Sex Gene Dosage in a Reptile

Published:2007-04-20 Issue:5823 Volume:316 Page:411-411
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Quinn Alexander E.¹²,Georges Arthur¹²,Sarre Stephen D.¹²,Guarino Fiorenzo¹²,Ezaz Tariq¹²,Graves Jennifer A. Marshall¹²

Affiliation:

1. Institute for Applied Ecology, University of Canberra, ACT 2601, Australia.

2. Comparative Genomics Group, Research School of Biological Sciences, Australian National University, Canberra, ACT 0200, Australia.

Abstract

Sex in reptiles is determined by genes on sex chromosomes or by incubation temperature. Previously these two modes were thought to be distinct, yet we show that high incubation temperatures reverse genotypic males (ZZ) to phenotypic females in a lizard with ZZ and ZW sex chromosomes. Thus, the W chromosome is not necessary for female differentiation. Sex determination is probably via a dosage-sensitive male-determining gene on the Z chromosome that is inactivated by extreme temperatures. Our data invite a novel hypothesis for the evolution of temperature-dependent sex determination (TSD) and suggest that sex chromosomes may exist in many TSD reptiles.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference8 articles.

1. Evolution of Sex Determining Mechanisms 1983

2. Temperature-Dependent Sex Determination in Vertebrates 2004

3. S. D. Sarre, A. Georges, A. Quinn, Bioessays26, 639 (2004).

4. T. Ezaz et al., Chromosome Res.13, 763 (2005).

5. Materials and methods are available on Science Online.

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