Comment on “Mechanism of eukaryotic RNA polymerase III transcription termination”-Reference-Cited by-同舟云学术

Comment on “Mechanism of eukaryotic RNA polymerase III transcription termination”

Published:2014-08 Issue:6196 Volume:345 Page:524-524
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Arimbasseri Aneeshkumar G.¹,Kassavetis George A.²,Maraia Richard J.¹³

Affiliation:

1. Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

2. Division of Biological Sciences, University of California, San Diego, CA, USA.

3. Commissioned Corps, U.S. Public Health Service.

Abstract

Nielsen et al . (Reports, 28 June 2013, p. 1577) characterized their RNA polymerase III (Pol III) preparation and concluded that it requires an RNA hairpin/duplex structure for terminating transcription. We could not corroborate their findings using bona fide Pol III from two laboratory sources. We show that Pol III efficiently terminates transcription in the absence of a hairpin/duplex in vitro and in vivo.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference15 articles.

1. Mechanism of Eukaryotic RNA Polymerase III Transcription Termination

2. Nucleotide sequences in Xenopus 5S DNA required for transcription termination

3. Termination of transcription by RNA polymerase III from wheat germ.

4. Distinguishing Core and Holoenzyme Mechanisms of Transcription Termination by RNA Polymerase III

5. Analysis of RNA Chain Elongation and Termination by Saccharomyces cerevisiae RNA Polymerase III

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