Mitochondrial Dysfunction and Type 2 Diabetes-Reference-Cited by-同舟云学术

Mitochondrial Dysfunction and Type 2 Diabetes

Published:2005-01-21 Issue:5708 Volume:307 Page:384-387
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lowell Bradford B.¹²,Shulman Gerald I.¹²

Affiliation:

1. Department of Medicine, Beth Israel Deaconess Medical Center, 99 Brookline Avenue, Harvard Medical School, Boston, MA 02215, USA.

2. Howard Hughes Medical Institute, Department of Internal Medicine and Department of Cellular and Molecular Physiology, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06536, USA.

Abstract

Maintenance of normal blood glucose levels depends on a complex interplay between the insulin responsiveness of skeletal muscle and liver and glucose-stimulated insulin secretion by pancreatic β cells. Defects in the former are responsible for insulin resistance, and defects in the latter are responsible for progression to hyperglycemia. Emerging evidence supports the potentially unifying hypothesis that both of these prominent features of type 2 diabetes are caused by mitochondrial dysfunction.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference59 articles.

1. Economic Costs of Diabetes in the U.S. in 2002

2. Global and societal implications of the diabetes epidemic

3. S. Lillioja et al., N. Engl. J. Med.318, 1217 (1988).

4. S. Lillioja et al., N. Engl. J. Med.329, 1988 (1993).

5. R. A. DeFronzo, R. C. Bonadonna, E. Ferrannini, Diabetes Care15, 318 (1992).

Cited by 1701 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Harmonization of experimental procedures to assess mitochondrial respiration in human permeabilized skeletal muscle fibers;Free Radical Biology and Medicine;2024-10

2. Development of a high quantum yield probe for detection of mitochondrial G-quadruplexes in live cells based on fluorescence lifetime imaging microscopy;Bioorganic & Medicinal Chemistry;2024-09

3. Mitochondrial Biomarkers and Metabolic Syndrome in Bipolar Disorder;Psychiatry Research;2024-09

4. Synthesis and anti-proliferative effect of novel 4-Aryl-1, 3-Thiazole-TPP conjugates via mitochondrial uncoupling process;Bioorganic Chemistry;2024-09

5. Exercise as a tool to mitigate metabolic disease;American Journal of Physiology-Cell Physiology;2024-09-01