Affiliation:
1. Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas (UMH-CSIC), Sant Joan d’Alacant, Spain.
Abstract
Brain map of touch sensation
The brain's somatosensory cortex contains a topographical map that reflects touch sensation inputs. During embryonic development, axons from the midbrain thalamus build columnar connections to the cortex in the absence of sensory input. Working in mice, Antón-Bolaños
et al.
found that these thalamocortical connections are responsible for organizing the somatosensory cortex (see the Perspective by Tiriac and Feller). Organization of the map in the cortex depends on spontaneous calcium waves in the embryonic thalamus. Thus, the somatosensory map is sketched out before actual sensory input begins to refine the details.
Science
, this issue p.
987
; see also p.
933
Funder
H2020 European Research Council
Hjärnfonden
Vetenskapsrådet
Agencia Estatal de Investigación
Ministry of Science, Innovation and Universities
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
132 articles.
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