A G Protein Mutant That Inhibits Thrombin and Purinergic Receptor Activation of Phospholipase A 2-Reference-Cited by-同舟云学术

A G Protein Mutant That Inhibits Thrombin and Purinergic Receptor Activation of Phospholipase A 2

Published:1990-08-10 Issue:4969 Volume:249 Page:662-666
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Gupta Sunil K.¹,Diez Emilio²,Heasley Lynn E.¹,Osawa Shoji¹,Johnson Gary L.¹

Affiliation:

1. Division of Basic Sciences, National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80206, and Department of Pharmacology, University of Colorado Medical School, Denver, CO 80262.

2. Smith,, Kline and Beecham Pharmaceuticals, Department of Immunologv, King of Prussia, PA 19406-0930.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference27 articles.

1. AXELROD, J, RECEPTOR-MEDIATED ACTIVATION OF PHOSPHOLIPASE-A2 VIA GTP-BINDING PROTEINS - ARACHIDONIC-ACID AND ITS METABOLITES AS 2ND MESSENGERS, TRENDS IN NEUROSCIENCES 11: 117 (1988).

2. BERRIDGE, M.J., CHANGES IN THE LEVELS OF INOSITOL PHOSPHATES AFTER AGONIST-DEPENDENT HYDROLYSIS OF MEMBRANE PHOSPHOINOSITIDES, BIOCHEMICAL JOURNAL 212: 473 (1983).

3. BLOCH, D.B., THE G-PROTEIN ALPHA-0-SUBUNIT ALTERS MORPHOLOGY, GROWTH-KINETICS, AND PHOSPHOLIPID-METABOLISM OF SOMATIC-CELLS, MOLECULAR AND CELLULAR BIOLOGY 9: 5434 (1989).

4. BURCH, R.M., PHOSPHOLIPASE-A2 AND PHOSPHOLIPASE-C ARE ACTIVATED BY DISTINCT GTP-BINDING PROTEINS IN RESPONSE TO ALPHA-1-ADRENERGIC STIMULATION IN FRTL5 THYROID-CELLS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 7201 (1986).

5. CERIONE, R.A., MECHANISM OF GUANINE-NUCLEOTIDE REGULATORY PROTEIN-MEDIATED INHIBITION OF ADENYLATE-CYCLASE - STUDIES WITH ISOLATED SUBUNITS OF TRANSDUCIN IN A RECONSTITUTED SYSTEM, JOURNAL OF BIOLOGICAL CHEMISTRY 261: 9514 (1986).

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