Characterization of Mammalian Selenoproteomes-Reference-Cited by-同舟云学术

Characterization of Mammalian Selenoproteomes

Published:2003-05-30 Issue:5624 Volume:300 Page:1439-1443
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Kryukov Gregory V.¹²,Castellano Sergi¹²,Novoselov Sergey V.¹²,Lobanov Alexey V.¹²,Zehtab Omid¹²,Guigó Roderic¹²,Gladyshev Vadim N.¹²

Affiliation:

1. Department of Biochemistry, University of Nebraska, Lincoln, NE 68588–0664, USA.

2. Grup de Recerca en Informàtica Biomèdica, Institut Municipal d'Investigació Mèdica, Universitat Pompeu Fabra, Centre de Regulació Genòmica, Doctor Aiguader 80, 08003 Barcelona, Catalonia, Spain.

Abstract

In the genetic code, UGA serves as a stop signal and a selenocysteine codon, but no computational methods for identifying its coding function are available. Consequently, most selenoprotein genes are misannotated. We identified selenoprotein genes in sequenced mammalian genomes by methods that rely on identification of selenocysteine insertion RNA structures, the coding potential of UGA codons, and the presence of cysteine-containing homologs. The human selenoproteome consists of 25 selenoproteins.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference30 articles.

1. A. Bock, Biofactors11, 77 (2000).

2. S. C. Low, M. J. Berry, Trends. Biochem. Sci.21, 203 (1996).

3. D. L. Hatfield, V. N. Gladyshev, Mol. Cell. Biol.22, 3565 (2002).

4. L. Cataldo et al., Mol. Reprod. Dev.45, 320 (1996).

5. V. N. Gladyshev, K.-T. Jeang, T. C. Stadtman, Proc. Natl. Acad. Sci. U.S.A.93, 6146 (1996).

Cited by 1977 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Risk assessment and impact prediction of associated heavy metal pollution in selenium-rich farmland;Science of The Total Environment;2024-11

2. Green and efficient choline hydroxide-promoted C(sp3)-H selenation of arylacetamides at room temperature;Molecular Catalysis;2024-10

3. Ferroptosis: Molecular perspective, cellular influence, cancer manifestation, and therapeutic potentials;Journal of Drug Delivery Science and Technology;2024-10

4. Evaluation of the effect of iron, zinc and selenium on metabolic processes in viral diseases;Experimental and Clinical Physiology and Biochemistry;2024-09-04

5. An epigenome-wide study of selenium status and DNA methylation in the Strong Heart Study;Environment International;2024-09