Plasmodium Chloroquine Resistance and the Search for a Replacement Antimalarial Drug-Reference-Cited by-同舟云学术

Plasmodium Chloroquine Resistance and the Search for a Replacement Antimalarial Drug

Published:2002-10-04 Issue:5591 Volume:298 Page:124-126
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Wellems Thomas E.¹

Affiliation:

1. Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.

Abstract

Genetic and biochemical research is providing new information on the mechanism of chloroquine resistance. Drug discovery initiatives are finding new leads that have favorable pharmaceutical properties and efficacy against chloroquine-resistant malaria.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference23 articles.

1. The public health impact of chloroquine resistance in Africa

2. Evidence for Different Mechanisms of Chloroquine Resistance in 2PlasmodiumSpecies That Cause Human Malaria

3. Chloroquine-resistant Plasmodium malariae in south Sumatra, Indonesia

4. Genome sequence of the human malaria parasite Plasmodium falciparum

5. An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

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