Affiliation:
1. Paul Berg is the Cahill Professor of Biochemistry, Emeritus, at the Stanford University School of Medicine, Palo Alto, CA. He received the Nobel Prize in Chemistry in 1980 and was an organizer of the Asilomar conference on recombinant DNA in 1975.
Abstract
Scientists are increasingly able to create genetically modified microorganisms whose properties are perceived as being beneficial as well as potentially useful for malevolent purposes. In 2004, a committee of the U.S. National Academy of Sciences adopted the term “dual use” for instances in which genetic or biosynthetic manipulations create new microorganisms, which, although valuable scientifically, are susceptible to misuse.
*
The premise was that the prospects for malevolent outcomes derive from deliberate actions to inflict specific or widespread harm. But in those and subsequent discussions, too little attention was given to the likelihood of an accidental laboratory release of modified agents that would allow them to spread in susceptible human populations. Recent research with a highly pathogenic influenza virus has highlighted the importance of this issue. Reviews of the influenza research concluded that given “the risk of accidental or malicious release,” the benefits of such studies must be well justified.
†
Thus, specific guidelines must be enforced to thwart not only intentionally harmful outcomes but accidental releases as well.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献