Discovery of Swine as a Host for the Reston ebolavirus

Author:

Barrette Roger W.1,Metwally Samia A.1,Rowland Jessica M.1,Xu Lizhe1,Zaki Sherif R.2,Nichol Stuart T.2,Rollin Pierre E.2,Towner Jonathan S.2,Shieh Wun-Ju2,Batten Brigid2,Sealy Tara K.2,Carrillo Consuelo1,Moran Karen E.1,Bracht Alexa J.1,Mayr Gregory A.1,Sirios-Cruz Magdalena3,Catbagan Davinio P.3,Lautner Elizabeth A.1,Ksiazek Thomas G.2,White William R.1,McIntosh Michael T.1

Affiliation:

1. Foreign Animal Disease Diagnostic Laboratory, National Veterinary Services Laboratories, Animal and Plant Health Inspection Services, United States Department of Agriculture, Plum Island Animal Disease Center, New York, NY 11944, USA.

2. Special Pathogens and Infectious Disease Pathology Branches, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

3. Bureau of Animal Industry, Department of Agriculture, Quezon City 1101, Philippines.

Abstract

Not Reston at All Reston ebolavirus is named, mistakenly perhaps, for Reston, Virginia, where it was discovered in the 1970s in imported macaques. After some alarm it was found not to be virulent in humans, uniquely among the ebola viruses, which are characteristically fatal causing a horrific spectrum of symptoms. Using a panviral detection assay, Reston ebolavirus has been rediscovered by Barrette et al. (p. 204 ) in domesticated pigs in the Philippines in association with other viruses that cause respiratory illness. The strains involved are closely related to the original macaque strain and, given how little variance there is among the viruses, it appears that it is freely circulating between these species possibly, like several other zoonotic viruses, having a reservoir in bats. Serological assays indicated that farm workers have become infected, although no obvious symptoms of human disease have been reported.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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