Comment on “Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome”-Reference-Cited by-同舟云学术

Comment on “Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome”

Published:2010-05-14 Issue:5980 Volume:328 Page:825-825
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Sudlow Cathie¹²,Macleod Malcolm¹³,Salman Rustam Al-Shahi¹,Stone Jon¹

Affiliation:

1. Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK

2. Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK

3. Department of Neurology, NHS Forth Valley, Stirling, UK

Abstract

Lombardi et al . (Reports, 23 October 2009, p. 585) reported an association between the human gammaretrovirus XMRV and chronic fatigue syndrome. However, their results may be misleading because of various potential sources of bias and confounding. If real, the association may lack generalizability because of the specific characteristics of the cases studied and could be due to reverse causality.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference6 articles.

1. Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome

2. Case-control studies: research in reverse

3. Compared to what? Finding controls for case-control studies

4. Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

5. Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome

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2. Chronic Fatigue Syndrome: 3 Cases and a Discussion of the Natural History of Attention-Deficit/Hyperactivity Disorder;Postgraduate Medicine;2013-01

3. The tale of xenotropic murine leukemia virus-related virus;Journal of General Virology;2012-05-01

4. XMRV and CFS—the sad end of a story;The Lancet;2012-02

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