Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping

Author:

Rommens Johanna M.1,Iannuzzi Michael C.2,Kerem Bat-Sheva1,Drumm Mitchell L.2,Melmer Georg1,Dean Michael3,Rozmahel Richard1,Cole Jeffery L.2,Kennedy Dara1,Hidaka Noriko2,Zsiga Martha1,Buchwald Manuel14,Tsui Lap-Chee14,Riordan John R.5,Collins Francis S.2

Affiliation:

1. Department of Genetics, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada.

2. Howard Hughes Medical Institute and Departments of Internal Medicine and Human Genetics, University of Michigan, Ann Arbor, MI 48109.

3. Program Resources, Inc., Frederick Cancer Research Facility, Frederick, MD 21701.

4. Departments of Medical Genetics and Medical Biophysics, University of Toronto, Toronto M5S 1A8, Canada.

5. Department of Biochemistry, Research Institute, The Hospital for Sick Children, Toronto, and the Departments of Biochemistry and Clinical Biochemistry, University of Toronto, Toronto M5S 1A8, Canada.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference74 articles.

1. ARFIN, S.M., ASSIGNMENT OF STRUCTURAL GENE FOR ASPARAGINE SYNTHETASE TO HUMAN CHROMOSOME-7, SOMATIC CELL GENETICS 9: 517 (1983).

2. BARKER, D, GENETIC-LINKAGE MAP OF HUMAN CHROMOSOME-7 WITH 63 DNA MARKERS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84: 8006 (1987).

3. BARTELS, I, REGIONAL MAPPING OF 6 CLONED DNA-SEQUENCES ON HUMAN CHROMOSOME-7, AMERICAN JOURNAL OF HUMAN GENETICS 38: 280 (1986).

4. BEAUDET, A, LINKAGE OF CYSTIC-FIBROSIS TO 2 TIGHTLY LINKED DNA MARKERS - JOINT REPORT FROM A COLLABORATIVE STUDY, AMERICAN JOURNAL OF HUMAN GENETICS 39: 681 (1986).

5. BERGER, W, CROSSOVERS IN 2 GERMAN CYSTIC-FIBROSIS FAMILIES DETERMINE PROBE ORDER FOR MET, 7C22 AND XV-2C/CS.7, HUMAN GENETICS 77: 197 (1987).

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