Switch of CD8 T Cells to Noncytolytic CD8 - CD4 - Cells that Make T H 2 Cytokines and Help B Cells

Author:

Erard François1,Wild Marie-Thérèse1,Garcia-Sanz Jose A.2,Le Gros Graham1

Affiliation:

1. Department of Allergy/Immunology, Pharmaceuticals Research Division, Ciba-Geigy Ltd., Basel, Switzerland.

2. Basel Institute for Immunology, Grenzacherstrasse 487, CH-4005 Basel, Switzerland

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference25 articles.

1. ABRAHAM, V.S., MECHANISM OF PROTECTION FROM GRAFT-VERSUS-HOST DISEASE MORTALITY BY IL-2 .3. EARLY REDUCTIONS IN DONOR T-CELL SUBSETS AND EXPANSION OF A CD3+CD4-CD8- CELL-POPULATION, JOURNAL OF IMMUNOLOGY 148: 3746 (1992).

2. ALONSO, S, COMPARISON OF 3 ACTIN-CODING SEQUENCES IN THE MOUSE - EVOLUTIONARY RELATIONSHIPS BETWEEN THE ACTIN GENES OF WARM-BLOODED VERTEBRATES, JOURNAL OF MOLECULAR EVOLUTION 23: 11 (1986).

3. CEROTTINI, J.C., GENERATION OF CYTOTOXIC T LYMPHOCYTES INVITRO .1. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN-CELLS IN MIXED LEUKOCYTE-CULTURES, JOURNAL OF EXPERIMENTAL MEDICINE 140: 703 (1974).

4. ERARD, F, DIFFERENTIAL REQUIREMENTS FOR THE INDUCTION OF INTERLEUKIN-2 RESPONSIVENESS IN L3T4+ AND LYT-2+ T-CELL SUBSETS, JOURNAL OF EXPERIMENTAL MEDICINE 162: 1738 (1985).

5. ERARD, F, INTERLEUKIN-2 IS BOTH NECESSARY AND SUFFICIENT FOR THE GROWTH AND DIFFERENTIATION OF LECTIN-STIMULATED CYTOLYTIC LYMPHOCYTE-T PRECURSORS, JOURNAL OF IMMUNOLOGY 134: 1644 (1985).

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