Transgenerational Epigenetic Instability Is a Source of Novel Methylation Variants-Reference-Cited by-同舟云学术

Transgenerational Epigenetic Instability Is a Source of Novel Methylation Variants

Published:2011-10-21 Issue:6054 Volume:334 Page:369-373
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Schmitz Robert J.¹²,Schultz Matthew D.¹²³,Lewsey Mathew G.¹²,O’Malley Ronan C.²,Urich Mark A.¹²,Libiger Ondrej⁴,Schork Nicholas J.⁴,Ecker Joseph R.¹²⁵

Affiliation:

1. Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

2. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

3. Bioinformatics Program, University of California at San Diego, La Jolla, CA 92093, USA.

4. The Scripps Translational Science Institute and the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

5. Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Abstract

Spontaneous methylation rates that may affect phenotype in the plant Arabidopsis are higher than the mutation rate.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Establishing, maintaining and modifying DNA methylation patterns in plants and animals

2. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

3. Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis

4. Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis

5. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription

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