Affiliation:
1. Institut Curie, UMR144 du Centre Nationale de la Recherche Scientifique, 26 rue d’Ulm, 75248 Paris Cedex 05, France.
Abstract
Centrosome Center Stage?
The centrosome is a major organizer of the cytoskeleton in animal cells. The precise duplication of this organelle at each cell cycle ensures proper organization of the mitotic apparatus and chromosome segregation. However, centrosomes are dispensable for cell division during some stages of development in mouse and
Drosophila
.
Bornens
(p.
422
) reviews the role of the centrosome in a variety of organisms and discusses how and why they can be dispensed with on occasion. In this vein,
Azimzadeh
et al.
(p.
461
, published online 5 January) now demonstrate that centrosomes in Planarian flatworms, best known for their remarkable regeneration abilities, are completely dispensable for both cell division and development.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
400 articles.
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