Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

Author:

Michaud Mickaël123,Martins Isabelle123,Sukkurwala Abdul Qader123,Adjemian Sandy123,Ma Yuting2345,Pellegatti Patrizia6,Shen Shensi123,Kepp Oliver123,Scoazec Marie27,Mignot Grégoire89,Rello-Varona Santiago123,Tailler Maximilien123,Menger Laurie123,Vacchelli Erika123,Galluzzi Lorenzo123,Ghiringhelli François89,di Virgilio Francesco6,Zitvogel Laurence2345,Kroemer Guido1291011

Affiliation:

1. INSERM, U848, Villejuif, France.

2. Institut Gustave Roussy, Villejuif, France.

3. Université Paris Sud, Faculté de Médecine Paris XI, Le Kremlin Bicêtre, France.

4. INSERM, U1015, Villejuif, France.

5. Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 507, Villejuif, France.

6. Department of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, Ferrara, Italy.

7. Metabolomics Platform, Institut Gustave Roussy, Villejuif, France.

8. Department of Medical Oncology, Georges François Leclerc Center, Dijon, France.

9. INSERM Avenir Team INSERM, CRI-866 University of Burgundy, Dijon, France.

10. Centre de Recherche des Cordeliers, Paris, France.

11. Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.

Abstract

The release of adenosine triphosphate through autophagy can promote antitumor immune responses.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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