NDR1 , a Pathogen-Induced Component Required for Arabidopsis Disease Resistance

Author:

Century Karen S.12,Shapiro Allan D.12,Repetti Peter P.12,Dahlbeck Douglas12,Holub Eric12,Staskawicz Brian J.12

Affiliation:

1. K. S. Century, A. D. Shapiro, P. P. Repetti, D. Dahlbeck, B. J. Staskawicz, Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720–3102, USA.

2. E. Holub, Plant Pathology and Weed Science Department, Horticulture Research International–Wellesbourne, Warwickshire CV35 9EF, UK.

Abstract

Plant disease resistance ( R ) genes confer an ability to resist infection by pathogens expressing specific corresponding avirulence genes. In Arabidopsis thaliana , resistance to both bacterial and fungal pathogens, mediated by several R gene products, requires the NDR1 gene. Positional cloning was used to isolate NDR1 , which encodes a 660–base pair open reading frame. The predicted 219–amino acid sequence suggests that NDR1 may be associated with a membrane. NDR1 expression is induced in response to pathogen challenge and may function to integrate various pathogen recognition signals.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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