The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome-Reference-Cited by-同舟云学术

The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome

Published:2004-04-09 Issue:5668 Volume:304 Page:304-307
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Dietrich Fred S.¹²³⁴,Voegeli Sylvia¹²³⁴,Brachat Sophie¹²³⁴,Lerch Anita¹²³⁴,Gates Krista¹²³⁴,Steiner Sabine¹²³⁴,Mohr Christine¹²³⁴,Pöhlmann Rainer¹²³⁴,Luedi Philippe¹²³⁴,Choi Sangdun¹²³⁴,Wing Rod A.¹²³⁴,Flavier Albert¹²³⁴,Gaffney Thomas D.¹²³⁴,Philippsen Peter¹²³⁴

Affiliation:

1. Biozentrum der Universität Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland.

2. Department of Molecular Genetics and Microbiology, Duke University Medical Center, Research Drive, Durham, NC 27710, USA.

3. Syngenta Biotechnology Inc., 3054 Cornwallis Road, Research Triangle Park, NC 27709, USA.

4. Departments of Agronomy and Biological Sciences, Clemson University, Clemson, SC 29634, USA.

Abstract

We have sequenced and annotated the genome of the filamentous ascomycete Ashbya gossypii . With a size of only 9.2 megabases, encoding 4718 protein-coding genes, it is the smallest genome of a free-living eukaryote yet characterized. More than 90% of A. gossypii genes show both homology and a particular pattern of synteny with Saccharomyces cerevisiae . Analysis of this pattern revealed 300 inversions and translocations that have occurred since divergence of these two species. It also provided compelling evidence that the evolution of S. cerevisiae included a whole genome duplication orfusion of two related species and showed, through inferred ancient gene orders, which of the duplicated genes lost one copy and which retained both copies.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

1. Three biotechnical processes using Ashbya gossypii, Candida famata, or Bacillus subtilis compete with chemical riboflavin production

2. Replicative transformation of the filamentous fungus Ashbya gossypii with plasmids containing Saccharomyces cerevisiae ARS elements

3. Homologous recombination as the main mechanism for DNA integration and cause of rearrangements in the filamentous ascomycete Ashbya gossypii.

4. A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii

5. PCR-based gene targeting in the filamentous fungus Ashbya gossypii

Cited by 571 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Intrinsically disordered sequences can tune fungal growth and the cell cycle for specific temperatures;Current Biology;2024-08

2. Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogenCryptococcus neoformans;2024-07-29

3. Metabolic engineering of Saccharomyces cerevisiae for the biosynthesis of a fungal pigment from the phytopathogenic fungus Cladosporium phlei;Journal of Biological Engineering;2024-05-13

4. M-O-M mediated denaturation resistant P2 tetramer on the infected erythrocyte surface of malaria parasite imports serum fatty acids;iScience;2024-05

5. Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts;Science;2024-04-26