Chromatin “Prepattern” and Histone Modifiers in a Fate Choice for Liver and Pancreas-Reference-Cited by-同舟云学术

Chromatin “Prepattern” and Histone Modifiers in a Fate Choice for Liver and Pancreas

Published:2011-05-20 Issue:6032 Volume:332 Page:963-966
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Xu Cheng-Ran¹,Cole Philip A.²,Meyers David J.²,Kormish Jay¹,Dent Sharon³,Zaret Kenneth S.¹

Affiliation:

1. Institute for Regenerative Medicine, Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

2. Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

3. Department of Molecular Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Smithville, TX 78957, USA.

Abstract

Screening histone modifications reveals distinctive patterns of chromatin marks for liver and pancreas development.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Link

http://www.sciencemag.org/content/332/6032/963.full.pdf

Reference37 articles.

1. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

2. A unique chromatin signature uncovers early developmental enhancers in humans

3. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells

4. A rapid micro chromatin immunoprecipitation assay (ChIP)

5. A bipotential precursor population for pancreas and liver within the embryonic endoderm

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