Comment on "Ongoing Adaptive Evolution of ASPM , a Brain Size Determinant in Homo sapiens "-Reference-Cited by-同舟云学术

Comment on "Ongoing Adaptive Evolution of ASPM , a Brain Size Determinant in Homo sapiens "

Published:2007-04-20 Issue:5823 Volume:316 Page:370-370
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Yu Fuli¹²³⁴⁵,Hill R. Sean¹²³⁴⁵,Schaffner Stephen F.¹²³⁴⁵,Sabeti Pardis C.¹²³⁴⁵,Wang Eric T.¹²³⁴⁵,Mignault Andre A.¹²³⁴⁵,Ferland Russell J.¹²³⁴⁵,Moyzis Robert K.¹²³⁴⁵,Walsh Christopher A.¹²³⁴⁵,Reich David¹²³⁴⁵

Affiliation:

1. Department of Genetics, Harvard Medical School, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

2. Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.

3. Division of Neurogenetics and Howard Hughes Medical Institute, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

4. Division of Genetics, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.

5. Department of Biological Chemistry, College of Medicine, University of California, Irvine, CA 92697, USA.

Abstract

Mekel-Bobrov et al . (Reports, 9 September 2005, p. 1720) suggested that ASPM , a gene associated with microcephaly, underwent natural selection within the last 500 to 14,100 years. Their analyses based on comparison with computer simulations indicated that ASPM had an unusual pattern of variation. However, when we compare ASPM empirically to a large number of other loci, its variation is not unusual and does not support selection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference16 articles.

1. Ongoing Adaptive Evolution of ASPM , a Brain Size Determinant in Homo sapiens

2. Positive Natural Selection in the Human Lineage

3. Materials and methods are available as supporting material on Science Online.

4. A haplotype map of the human genome

5. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression;2023-06-01

2. Super Dense Coding with Dark-Soliton Qubits;International Journal of Theoretical Physics;2022-02

3. Entanglement sudden death with quasi-static approximation;The European Physical Journal Plus;2022-02

4. Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition;Genome Research;2021-01-13

5. Do Genes Associated with Dyslexia of Chinese Characters Evolve Neutrally?;Genes;2020-06-17