Neural Computing in Cancer Drug Development: Predicting Mechanism of Action-Reference-Cited by-同舟云学术

Neural Computing in Cancer Drug Development: Predicting Mechanism of Action

Published:1992-10-16 Issue:5081 Volume:258 Page:447-451
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Weinstein John N.¹,Kohn Kurt W.²,Grever Michael R.³,Viswanadhan Vellarkad N.¹,Rubinstein Lawrence V.⁴,Monks Anne P.⁵,Scudiero Dominic A.⁵,Welch Lester⁵,Koutsoukos Antonis D.⁴,Chiausa August J.⁶,Paull Kenneth D.⁶

Affiliation:

1. Laboratory of Mathematical Biology, Division of Cancer Biology, National Cancer Institute, Bethesda, MD 20892.

2. Laboratory of Molecular Pharmacology, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, MD 20892.

3. Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, MD 20892.

4. Biometric Research Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, MD 20892.

5. Program Resources, Inc./DynCorp., National Cancer Institute/ Frederick Cancer Research and Development Center, Frederick, MD 21702.

6. Information Technology Branch, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Bethesda, MD 20892.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference34 articles.

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2. ALLEY, M.C., FEASIBILITY OF DRUG SCREENING WITH PANELS OF HUMAN-TUMOR CELL-LINES USING A MICROCULTURE TETRAZOLIUM ASSAY, CANCER RESEARCH 48: 589 (1988).

3. ASADA, N, POTENTIAL USEFULNESS OF AN ARTIFICIAL NEURAL NETWORK FOR DIFFERENTIAL-DIAGNOSIS OF INTERSTITIAL LUNG-DISEASES - PILOT-STUDY, RADIOLOGY 177: 857 (1990).

4. BAI, R, HALICHONDRIN-B AND HOMOHALICHONDRIN-B, MARINE NATURAL-PRODUCTS BINDING IN THE VINCA DOMAIN OF TUBULIN - DISCOVERY OF TUBULIN-BASED MECHANISM OF ACTION BY ANALYSIS OF DIFFERENTIAL CYTOTOXICITY DATA, JOURNAL OF BIOLOGICAL CHEMISTRY 266: 15882 (1991).

5. BOONE, J.M., NEURAL NETWORKS IN RADIOLOGY - AN INTRODUCTION AND EVALUATION IN A SIGNAL-DETECTION TASK, MEDICAL PHYSICS 17: 234 (1990).

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