The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling

Author:

Stegmann Martin1,Monaghan Jacqueline1,Smakowska-Luzan Elwira2,Rovenich Hanna1,Lehner Anita3,Holton Nicholas1,Belkhadir Youssef2,Zipfel Cyril1

Affiliation:

1. The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.

2. Gregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna Biocenter (VBC), 1030 Vienna, Austria.

3. Protein Technologies Facility, Vienna Biocenter Core Facilities (VBCF), Vienna, Austria.

Abstract

Small peptides allow rapid responses RALFs (rapid alkalinization factors), a family of small peptides in plants, are produced in response to rapidly changing conditions. Stegmann et al. studied the agility and diversity built into this signaling network. Some RALFs, such as RALF23 and its relative RALF33, are activated by proteolytic cleavage. Others, such as RALF32, are not. RALF23 and RALF33 are called into play after a pathogen triggers immune responses. RALF32, on the other hand, regulates seedling growth. All three of these RALFs use the same receptor kinase, which can interact with other signaling components. Thus, plant responses can be fine-tuned by rapid release of peptides. Science , this issue p. 287

Funder

Gatsby Charitable Foundation

European Research Council

Austrian Academy of Science

Deutsche Forschungsgemeinschaft

European Molecular Biology Organization

U.K. Biotechnology and Biological Sciences Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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