Micro-Optical Sectioning Tomography to Obtain a High-Resolution Atlas of the Mouse Brain-Reference-Cited by-同舟云学术

Micro-Optical Sectioning Tomography to Obtain a High-Resolution Atlas of the Mouse Brain

Published:2010-12-03 Issue:6009 Volume:330 Page:1404-1408
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Li Anan¹,Gong Hui¹,Zhang Bin¹,Wang Qingdi¹,Yan Cheng¹,Wu Jingpeng¹,Liu Qian¹,Zeng Shaoqun¹,Luo Qingming¹

Affiliation:

1. Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics–Huazhong University of Science and Technology, Wuhan 430074, P. R. China.

Abstract

Better Brain Maps A high-resolution atlas of the complete neuronal connectivity in a whole brain should fundamentally advance our understanding of the organization and function of animal nervous systems. Now, A. Li. et al. (p. 1404 , published online 4 November) describe an automated system, micro-optical sectioning tomography, that allowed three-dimensional mapping of the morphology and spatial location of neurons and traces of neurites in a whole, intact mouse brain.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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