Mutants of Pertussis Toxin Suitable for Vaccine Development

Author:

Pizza Mariagrazia1,Covacci Antonio1,Bartoloni Antonella1,Perugini Maria1,Nencioni Luciano1,De Magistris Maria Teresa1,Villa Luigi1,Nucci Daniele1,Manetti Roberto1,Bugnoli Massimo1,Giovannoni Franco1,Olivieri Roberto1,Barbieri Joseph T.2,Sato Hiroko3,Rappuoli Rino1

Affiliation:

1. Sclavo Research Center, Siena, Italy.

2. Department of Microbiology, Medical College of Wisconsin, Milwaukee, WI 53226.

3. National Institute of Health, Kamiosaki, Shinagawa-ku, Tokyo, Japan.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference45 articles.

1. LANCET 1: 955 (1988).

2. ANTONI, G, J IMMUNOL METHODS 61: 61 (1985).

3. ARICO, B, BORDETELLA-PARAPERTUSSIS AND BORDETELLA-BRONCHISEPTICA CONTAIN TRANSCRIPTIONALLY SILENT PERTUSSIS TOXIN GENES, JOURNAL OF BACTERIOLOGY 169: 2847 (1987).

4. BARBIERI, J.T., ADP-RIBOSYLTRANSFERASE MUTATIONS IN THE CATALYTIC S-1 SUBUNIT OF PERTUSSIS TOXIN, INFECTION AND IMMUNITY 56: 1934 (1988).

5. BARTOLONI, A, MAPPING OF A PROTECTIVE EPITOPE OF PERTUSSIS TOXIN BY INVITRO REFOLDING OF RECOMBINANT FRAGMENTS, BIO-TECHNOLOGY 6: 709 (1988).

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