Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics

Author:

Kim Tae-il12,McCall Jordan G.3456,Jung Yei Hwan1,Huang Xian1,Siuda Edward R.3456,Li Yuhang7,Song Jizhou8,Song Young Min1,Pao Hsuan An1,Kim Rak-Hwan1,Lu Chaofeng9,Lee Sung Dan10,Song Il-Sun11,Shin GunChul1,Al-Hasani Ream345,Kim Stanley1,Tan Meng Peun10,Huang Yonggang7,Omenetto Fiorenzo G.1213,Rogers John A.1101114,Bruchas Michael R.3456

Affiliation:

1. Department of Materials Science and Engineering, Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

2. School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 440-746, Korea.

3. Department of Anesthesiology, Division of Basic Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

4. Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

5. Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

6. Division of Biological and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.

7. Department of Civil and Environmental Engineering, Department of Mechanical Engineering, and Institute for Public Health and Medicine, Northwestern University, Evanston, IL 60208, USA.

8. Department of Mechanical and Aerospace Engineering, University of Miami, Coral Gables, FL 33146, USA.

9. Soft Matter Research Center and Department of Civil Engineering, Zhejiang University, 38 Zheda Road, Hangzhou 310027, China.

10. Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.

11. Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.

12. Department of Biomedical Engineering, Tufts University, Medford, MA 02115, USA.

13. Department of Physics, Tufts University, Medford, MA 02115, USA.

14. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.

Abstract

The Smaller, the Better New semiconductor device technology enables injection of light-emitting diodes, silicon devices, actuators, and sensors at precisely controlled locations within biological tissues, such as the brain. Kim et al. (p. 211 ) show how wireless control of animal models using these technologies and the techniques of optogenetics provide new insights into basic behavioral neuroscience.

Funder

Division of Materials Sciences U.S. Department of Energy

National Institute on Drug Abuse

National Institute of Neurological Disorders and Stroke

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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