MED12 , the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas-Reference-Cited by-同舟云学术

MED12 , the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

Published:2011-10-14 Issue:6053 Volume:334 Page:252-255
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Mäkinen Netta¹,Mehine Miika¹,Tolvanen Jaana¹,Kaasinen Eevi¹,Li Yilong¹,Lehtonen Heli J.¹,Gentile Massimiliano²,Yan Jian³,Enge Martin³,Taipale Minna¹³,Aavikko Mervi¹,Katainen Riku¹,Virolainen Elina⁴,Böhling Tom⁴⁵,Koski Taru A.¹,Launonen Virpi¹,Sjöberg Jari⁶,Taipale Jussi¹³,Vahteristo Pia¹,Aaltonen Lauri A.¹

Affiliation:

1. Department of Medical Genetics, Genome-Scale Biology Research Program, 00014 University of Helsinki, Helsinki, Finland.

2. Center for Science Ltd., 02101 Espoo, Finland.

3. Science for Life Laboratory, Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Stockholm, Sweden.

4. Department of Pathology, Haartman Institute, 00014 University of Helsinki, Helsinki, Finland.

5. Laboratory of Hospital District of Helsinki and Uusimaa, 00029 Helsinki University Central Hospital, Helsinki, Finland.

6. Department of Obstetrics and Gynecology, 00029 Helsinki University Central Hospital, Helsinki, Finland.

Abstract

Uterine fibroids frequently harbor mutations in a specific gene that has been implicated in transcriptional regulation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference28 articles.

1. Incidence, aetiology and epidemiology of uterine fibroids

2. Uterine fibroids

3. Uterine Myomas: An Overview of Development, Clinical Features, and Management

4. Nationwide Use of Laparoscopic Hysterectomy Compared With Abdominal and Vaginal Approaches

5. Diagnosing and preventing inheirted disease

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