1. Centre for Systems Biology, Samuel Lunenfeld Research Institute, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada.
2. Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
3. Department of Molecular Genetics, University of Toronto, 1 Kings College Circle, Toronto, Ontario, M5S 1A8, Canada.
4. Wellcome Trust Centre for Cell Biology and School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JR Scotland, UK.
5. Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
6. Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.