Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry-Reference-Cited by-同舟云学术

Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry

Published:2019-02-22 Issue:6429 Volume:363 Page:838-845
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Peters Byron K.¹^ORCID,Rodriguez Kevin X.¹,Reisberg Solomon H.¹,Beil Sebastian B.¹^ORCID,Hickey David P.²^ORCID,Kawamata Yu¹,Collins Michael³,Starr Jeremy³,Chen Longrui⁴,Udyavara Sagar⁵^ORCID,Klunder Kevin²^ORCID,Gorey Timothy J.²,Anderson Scott L.²^ORCID,Neurock Matthew⁵^ORCID,Minteer Shelley D.²^ORCID,Baran Phil S.¹^ORCID

Affiliation:

1. Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.

2. Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.

3. Discovery Sciences, Medicine Design, Pfizer Global Research and Development, Groton, CT 06340, USA.

4. Asymchem Life Science (Tianjin), Tianjin Economic-Technological Development Zone, Tianjin 300457, China.

5. Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA.

Abstract

Scaled-up sodium-free Birch reductions The so-called Birch reduction is frequently used by chemists despite its daunting conditions: Pyrophoric sodium is dissolved in pure liquified ammonia to achieve partial reduction of aromatics. Peters et al. surveyed and then optimized small-scale electrochemical alternatives to devise a safer protocol that can work on a larger scale with a broad range of functionally complex substrates. Science , this issue p. 838

Funder

National Science Foundation

National Institutes of Health

Swedish Research Council Formas

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference112 articles.

1. P. W. Rabideau Z. Marcinow “The Birch reduction of aromatic compounds ” in Organic Reactions Volume 42 L. A. Paquette Ed. (Wiley 1992) pp. 1–334.

2. Ir-Catalyzed Asymmetric and Regioselective Hydrogenation of Cyclic Allylsilanes and Generation of Quaternary Stereocenters via the Hosomi-Sakurai Allylation

3. Enantio- and Regioselective Ir-Catalyzed Hydrogenation of Di- and Trisubstituted Cycloalkenes