Identification of Envelope V3 Loop as the Major Determinant of CD4 Neutralization Sensitivity of HIV-1
Author:
Affiliation:
1. Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710.
2. Department of Surgery, Duke University Medical Center, Durham, NC 27710.
3. Howard Hughes Medical Institute, Section of Genetics,
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference48 articles.
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2. BRIGHTY, D.W., ENVELOPE PROTEINS FROM CLINICAL ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 THAT ARE REFRACTORY TO NEUTRALIZATION BY SOLUBLE CD4 POSSESS HIGH-AFFINITY FOR THE CD4 RECEPTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88: 7802 (1991).
3. BYRN, R.A., CHARACTERIZATION OF INVITRO INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS BY PURIFIED RECOMBINANT CD4, JOURNAL OF VIROLOGY 63: 4370 (1989).
4. Biologic Features of HIV-1 That Correlate with Virulence in the Host
5. CLAPHAM, P.R., SOLUBLE CD4 BLOCKS THE INFECTIVITY OF DIVERSE STRAINS OF HIV AND SIV FOR T-CELLS AND MONOCYTES BUT NOT FOR BRAIN AND MUSCLE-CELLS, NATURE 337: 368 (1989).
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