Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage

Author:

Fluckiger Aurélie12ORCID,Daillère Romain123,Sassi Mohamed4ORCID,Sixt Barbara Susanne56789ORCID,Liu Peng678910ORCID,Loos Friedemann678910ORCID,Richard Corentin111213ORCID,Rabu Catherine1415ORCID,Alou Maryam Tidjani1216,Goubet Anne-Gaëlle12ORCID,Lemaitre Fabien13ORCID,Ferrere Gladys12,Derosa Lisa1217ORCID,Duong Connie P. M.12ORCID,Messaoudene Meriem18,Gagné Andréanne18ORCID,Joubert Philippe18ORCID,De Sordi Luisa1920ORCID,Debarbieux Laurent19ORCID,Simon Sylvain1415ORCID,Scarlata Clara-Maria21ORCID,Ayyoub Maha21ORCID,Palermo Belinda22ORCID,Facciolo Francesco23,Boidot Romain24ORCID,Wheeler Richard25ORCID,Boneca Ivo Gomperts25ORCID,Sztupinszki Zsofia26ORCID,Papp Krisztian27ORCID,Csabai Istvan27ORCID,Pasolli Edoardo28ORCID,Segata Nicola29ORCID,Lopez-Otin Carlos7891030ORCID,Szallasi Zoltan26313233ORCID,Andre Fabrice3435ORCID,Iebba Valerio1236ORCID,Quiniou Valentin3738ORCID,Klatzmann David3738,Boukhalil Jacques16,Khelaifia Saber16,Raoult Didier16,Albiges Laurence139,Escudier Bernard13940ORCID,Eggermont Alexander141ORCID,Mami-Chouaib Fathia42,Nistico Paola2223ORCID,Ghiringhelli François43,Routy Bertrand1844ORCID,Labarrière Nathalie1415ORCID,Cattoir Vincent44546ORCID,Kroemer Guido678910ORCID,Zitvogel Laurence121747ORCID

Affiliation:

1. Gustave Roussy Cancer Campus (GRCC), Villejuif, France.

2. Institut National de la Santé et de la Recherche Médicale, U1015, Institut Gustave Roussy, Villejuif, France.

3. everImmune, Gustave Roussy Cancer Center, Villejuif, France.

4. Université Rennes 1, Laboratoire de Biochimie Pharmaceutique, Inserm U1230 - UPRES EA 2311, Rennes, France.

5. Laboratory for Molecular Infection Medicine Sweden, Umeå Centre for Microbial Research, Department of Molecular Biology, Umeå University, 90187, Umeå, Sweden.

6. Cell Biology and Metabolomics Platforms, Gustave Roussy Cancer Campus, Villejuif, France.

7. Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

8. INSERM U1138, Paris, France.

9. Université de Paris, Paris, France.

10. Sorbonne Université, Paris, France.

11. Research Platform in Biological Oncology, Dijon, France.

12. GIMI Genetic and Immunology Medical Institute, Dijon, France.

13. University of Burgundy-Franche Comté, Dijon, France.

14. CRCINA, INSERM, Université d'Angers, Université de Nantes, Nantes, France.

15. LabEx IGO “Immunotherapy, Graft, Oncology,” Nantes, France.

16. UMR MEPHI, Aix-Marseille Université, IRD, AP-HM, Institut Hospitalo-Universitaire Méditerranée-Infection, 19-21 Boulevard Jean Moulin, 13385, Marseille cedex 05, France.

17. Université Paris-Saclay, Villejuif, F-94805, France.

18. Institut Universitaire de Cardiologie et de Pneumologie de Québec, Research Center and Department of Cytology and Pathology, Québec City, Québec, Canada.

19. Bacteriophage, Bacterium, Host Laboratory, Institut Pasteur, F-75015 Paris, France.

20. Sorbonne Université, Centre de Recherche Saint Antoine, INSERM UMRS_938, Paris, France.

21. Cancer Research Centre of Toulouse, INSERM UMR 1037, 31037 Toulouse, France; Université Toulouse III Paul Sabatier, 31330 Toulouse, France; Institut Universitaire du Cancer de Toulouse-Oncopole, 31100 Toulouse, France.

22. Unit of Tumor Immunology and Immunotherapy, Department of Research, Advanced Diagnostics and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

23. Thoracic Surgery Unit, Department of Surgical Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

24. Unit of Molecular Biology, Department of Biology and Pathology of Tumors, Georges-François Leclerc Anticancer Center, UNICANCER, Dijon, France.

25. Institut Pasteur, Unit Biology and Genetics of the Bacterial Cell Wall, Paris, France.

26. Computational Health Informatics Program (CHIP), Boston Children's Hospital, Boston, MA, USA.

27. Department of Physics of Complex Systems, ELTE Eötvös Loránd University, Budapest, Hungary.

28. Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy.

29. Department CIBIO, University of Trento, Trento, Italy.

30. Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.

31. Harvard Medical School, Boston, MA, USA.

32. Danish Cancer Society Research Center, Copenhagen, Denmark.

33. MTA-SE-NAP, Brain Metastasis Research Group, 2nd Department of Pathology, Semmelweis University, Budapest, Hungary.

34. Department of Cancer Medicine, Breast Cancer Committee, Gustave Roussy, Villejuif, France.

35. INSERM Unit 981, Gustave Roussy, Villejuif, France.

36. Department of Medical Sciences, University of Trieste, 34137 Trieste, Italy.

37. AP-HP, Hôpital Pitié-Salpêtrière, Clinical Investigation Center in Biotherapy (CIC-BTi) and Immunology-Inflammation-Infectiology and Dermatology Department (3iD), F-75651, Paris, France.

38. Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), F-75651, Paris, France.

39. Department of Medical Oncology, Gustave Roussy, Villejuif, France.

40. INSERM U981, GRCC, Villejuif, France.

41. Princess Maxima Center, CS 3584 Utrecht, the Netherlands.

42. INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Fac. de Médecine - Univ. Paris-Sud, Université Paris-Saclay, 94805, Villejuif, France.

43. Department of Medical Oncology, Center GF Leclerc, Dijon, France.

44. Division d'Hémato-Oncologie, Département de Médicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.

45. CHU de Rennes - Hôpital Ponchaillou, Service de Bactériologie-Hygiène Hospitalière, Rennes, France.

46. CNR de la Résistance aux Antibiotiques (laboratoire associé 'Entérocoques'), Rennes, France.

47. Suzhou Institute for Systems Biology, Chinese Academy of Medical Sciences, Suzhou, China.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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